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Tryphaena is mentioned briefly in Rom.16.12 as one of the Christian women in Rome to whom Paul sends greetings. She is described as one who "worked hard in the Lord," indicating her dedication and service to the church. Paul's greeting suggests that Tryphaena was a prominent member of the Roman Christian community and had labored diligently for the cause of Christ. No other details are provided about her background or specific role in the church. The mention of Tryphaena, along with other women such as Tryphosa and Persis, highlights the significant contributions of women in the early church and their partnership in the gospel ministry.

Names, relations and descriptions from TIPNR by STEP Bible / Tyndale House Cambridge, CC BY 4.0